diff --git a/CHANGELOG.txt b/CHANGELOG.txt
index a2a7ce9c8b..bb7434979c 100644
--- a/CHANGELOG.txt
+++ b/CHANGELOG.txt
@@ -22,7 +22,7 @@ Changelog
 ~~~~~~~~~~~~~~~~~~
 
  * Fix: Prevent error when filtering by locale and searching with Elasticsearch (Sage Abdullah)
-
+ * Fix: Support searching `none()` querysets (Matt Westcott)
 
 6.4 (03.02.2025)
 ~~~~~~~~~~~~~~~~
diff --git a/docs/releases/6.4.1.md b/docs/releases/6.4.1.md
index 5bc1190c68..48972ce4df 100644
--- a/docs/releases/6.4.1.md
+++ b/docs/releases/6.4.1.md
@@ -14,3 +14,4 @@ depth: 1
 ### Bug fixes
 
  * Prevent error when filtering by locale and searching with Elasticsearch (Sage Abdullah)
+ * Support searching `none()` querysets (Matt Westcott)
diff --git a/wagtail/search/backends/base.py b/wagtail/search/backends/base.py
index f1ee7e2627..def91fda5f 100644
--- a/wagtail/search/backends/base.py
+++ b/wagtail/search/backends/base.py
@@ -5,7 +5,7 @@ from django.db.models.functions.datetime import Extract as ExtractDate
 from django.db.models.functions.datetime import ExtractYear
 from django.db.models.lookups import Lookup
 from django.db.models.query import QuerySet
-from django.db.models.sql.where import SubqueryConstraint, WhereNode
+from django.db.models.sql.where import NothingNode, SubqueryConstraint, WhereNode
 
 from wagtail.search.index import class_is_indexed, get_indexed_models
 from wagtail.search.query import MATCH_ALL, PlainText
@@ -69,6 +69,9 @@ class BaseSearchQueryCompiler:
     def _process_lookup(self, field, lookup, value):
         raise NotImplementedError
 
+    def _process_match_none(self):
+        raise NotImplementedError
+
     def _connect_filters(self, filters, connector, negated):
         raise NotImplementedError
 
@@ -179,6 +182,9 @@ class BaseSearchQueryCompiler:
                 field_attname, lookup, value, check_only=check_only
             )
 
+        elif isinstance(where_node, NothingNode):
+            return self._process_match_none()
+
         elif isinstance(where_node, SubqueryConstraint):
             raise FilterError(
                 "Could not apply filter on search results: Subqueries are not allowed."
diff --git a/wagtail/search/backends/database/fallback.py b/wagtail/search/backends/database/fallback.py
index e8cf203944..940c41b8bd 100644
--- a/wagtail/search/backends/database/fallback.py
+++ b/wagtail/search/backends/database/fallback.py
@@ -56,6 +56,9 @@ class DatabaseSearchQueryCompiler(BaseSearchQueryCompiler):
             **{field.get_attname(self.queryset.model) + "__" + lookup: value}
         )
 
+    def _process_match_none(self):
+        return models.Q(pk__in=[])
+
     def _connect_filters(self, filters, connector, negated):
         if connector == "AND":
             q = models.Q(*filters)
diff --git a/wagtail/search/backends/database/mysql/mysql.py b/wagtail/search/backends/database/mysql/mysql.py
index 94db1de72c..05b24f484d 100644
--- a/wagtail/search/backends/database/mysql/mysql.py
+++ b/wagtail/search/backends/database/mysql/mysql.py
@@ -522,6 +522,9 @@ class MySQLSearchQueryCompiler(BaseSearchQueryCompiler):
         lhs = field.get_attname(self.queryset.model) + "__" + lookup
         return Q(**{lhs: value})
 
+    def _process_match_none(self):
+        return Q(pk__in=[])
+
     def _connect_filters(self, filters, connector, negated):
         if connector == "AND":
             q = Q(*filters)
diff --git a/wagtail/search/backends/database/postgres/postgres.py b/wagtail/search/backends/database/postgres/postgres.py
index 7eab3c1e61..a30a7f27d8 100644
--- a/wagtail/search/backends/database/postgres/postgres.py
+++ b/wagtail/search/backends/database/postgres/postgres.py
@@ -561,6 +561,9 @@ class PostgresSearchQueryCompiler(BaseSearchQueryCompiler):
         lhs = field.get_attname(self.queryset.model) + "__" + lookup
         return Q(**{lhs: value})
 
+    def _process_match_none(self):
+        return Q(pk__in=[])
+
     def _connect_filters(self, filters, connector, negated):
         if connector == "AND":
             q = Q(*filters)
diff --git a/wagtail/search/backends/database/sqlite/sqlite.py b/wagtail/search/backends/database/sqlite/sqlite.py
index 67e77d0c12..d2f40bcb40 100644
--- a/wagtail/search/backends/database/sqlite/sqlite.py
+++ b/wagtail/search/backends/database/sqlite/sqlite.py
@@ -580,6 +580,9 @@ class SQLiteSearchQueryCompiler(BaseSearchQueryCompiler):
         lhs = field.get_attname(self.queryset.model) + "__" + lookup
         return Q(**{lhs: value})
 
+    def _process_match_none(self):
+        return Q(pk__in=[])
+
     def _connect_filters(self, filters, connector, negated):
         if connector == "AND":
             q = Q(*filters)
diff --git a/wagtail/search/backends/elasticsearch7.py b/wagtail/search/backends/elasticsearch7.py
index 6d5411e07c..f6e0c1e69a 100644
--- a/wagtail/search/backends/elasticsearch7.py
+++ b/wagtail/search/backends/elasticsearch7.py
@@ -565,6 +565,9 @@ class Elasticsearch7SearchQueryCompiler(BaseSearchQueryCompiler):
                 }
             }
 
+    def _process_match_none(self):
+        return {"bool": {"mustNot": {"match_all": {}}}}
+
     def _connect_filters(self, filters, connector, negated):
         if filters:
             if len(filters) == 1:
diff --git a/wagtail/search/tests/test_backends.py b/wagtail/search/tests/test_backends.py
index 33c5c65956..ab84acdeef 100644
--- a/wagtail/search/tests/test_backends.py
+++ b/wagtail/search/tests/test_backends.py
@@ -638,6 +638,13 @@ class BackendTests(WagtailTestUtils):
             ],
         )
 
+    def test_filter_none(self):
+        results = self.backend.search(MATCH_ALL, models.Book.objects.none())
+        self.assertListEqual(list(results), [])
+
+        results = self.backend.search("JavaScript", models.Book.objects.none())
+        self.assertListEqual(list(results), [])
+
     # FACET TESTS
 
     def test_facet(self):