diff --git a/.github/workflows/ports_unix.yml b/.github/workflows/ports_unix.yml
index aa4b8abdc9..5c4a4f3047 100644
--- a/.github/workflows/ports_unix.yml
+++ b/.github/workflows/ports_unix.yml
@@ -186,3 +186,17 @@ jobs:
     - name: Print failures
       if: failure()
       run: tests/run-tests.py --print-failures
+
+  qemu_mips:
+    runs-on: ubuntu-latest
+    steps:
+    - uses: actions/checkout@v2
+    - name: Install packages
+      run: source tools/ci.sh && ci_unix_qemu_mips_setup
+    - name: Build
+      run: source tools/ci.sh && ci_unix_qemu_mips_build
+    - name: Run main test suite
+      run: source tools/ci.sh && ci_unix_qemu_mips_run_tests
+    - name: Print failures
+      if: failure()
+      run: tests/run-tests.py --print-failures
diff --git a/tools/ci.sh b/tools/ci.sh
index c986c9fef8..23e529e5e1 100755
--- a/tools/ci.sh
+++ b/tools/ci.sh
@@ -292,6 +292,13 @@ CI_UNIX_OPTS_SYS_SETTRACE_STACKLESS=(
     CFLAGS_EXTRA="-DMICROPY_STACKLESS=1 -DMICROPY_STACKLESS_STRICT=1 -DMICROPY_PY_SYS_SETTRACE=1"
 )
 
+CI_UNIX_OPTS_QEMU_MIPS=(
+    CROSS_COMPILE=mips-linux-gnu-
+    VARIANT=coverage
+    MICROPY_STANDALONE=1
+    LDFLAGS_EXTRA="-static"
+)
+
 function ci_unix_build_helper {
     make ${MAKEOPTS} -C mpy-cross
     make ${MAKEOPTS} -C ports/unix "$@" submodules
@@ -478,6 +485,26 @@ function ci_unix_macos_run_tests {
     (cd tests && ./run-tests.py --exclude 'uasyncio_(basic|heaplock|lock|wait_task)' --exclude 'import_pkg7.py' --exclude 'urandom_basic.py')
 }
 
+function ci_unix_qemu_mips_setup {
+    sudo apt-get update
+    sudo apt-get install gcc-mips-linux-gnu g++-mips-linux-gnu
+    sudo apt-get install qemu-user
+    qemu-mips --version
+}
+
+function ci_unix_qemu_mips_build {
+    # qemu-mips on GitHub Actions will seg-fault if not linked statically
+    ci_unix_build_helper "${CI_UNIX_OPTS_QEMU_MIPS[@]}"
+}
+
+function ci_unix_qemu_mips_run_tests {
+    # Issues with MIPS tests:
+    # - (i)listdir does not work, it always returns the empty list (it's an issue with the underlying C call)
+    # - ffi tests do not work
+    file ./ports/unix/micropython-coverage
+    (cd tests && MICROPY_MICROPYTHON=../ports/unix/micropython-coverage ./run-tests.py --exclude 'vfs_posix.py' --exclude 'ffi_(callback|float|float2).py')
+}
+
 ########################################################################################
 # ports/windows